WET AMD
Wet age-related macular degeneration (Wet AMD) is a progressive eye disease that can affect the macula, compromising central vision.
DL-AAA Induced Retinal Neovascularization
The DL-2-aminoadipic acid (AAA) model of chronic retinal neovascularization is used to evaluate the durability of test articles targeting wet age-related macular degeneration (wet AMD) and diabetic retinopathy through quantification of vascular leakage inhibition. Our team of experts has developed this model with consistent results in the Dutch Belted rabbit.
Laser-Induced Choroidal Neovascularization
The experimental laser-induced CNV model is used to evaluate the efficacy of test articles targeting wet age-related macular degeneration (wet AMD) and diabetic retinopathy. Our team of experts has developed reproducible models with consistent results in mice, rats and swine.
VEGF- Induced Retinal Leakage and Neovascularization
The VEGF-induced retinal leakage model is used to assess the efficacy of test articles targeting wet age-related macular degeneration (wet AMD) and diabetic retinopathy. Our team of experts has developed this model with consistent results in in the Dutch Belted rabbit.