Diabetic Retinopathy
Diabetic retinopathy is a diabetes-related complication that affects the retina, the light-sensitive tissue at the back of the eye. It's caused by damage to the blood vessels due to prolonged high blood sugar levels.
DL-AAA Induced Retinal Neovascularization
The DL-2-aminoadipic acid (AAA) model of RNV in Dutch Belted rabbits is used to evaluate therapeutic efficacy of test articles through quantification of vascular leakage inhibition. Our team of experts has developed this model with consistent results in the Dutch Belted rabbit.
Laser-Induced Choroidal Neovascularization
The experimental laser-induced CNV model was designed to assess the efficacy of test articles for conditions including wet age-related macular degeneration (wet AMD) and diabetic retinopathy. Our team of experts has developed reproducible models with consistent results in mice, rats and swine.
VEGF- Induced Retinal Leakage and Neovascularization
The VEGF-induced retinal leakage and neovascularization model was designed to assess the efficacy of test articles for the treatment of diabetic retinopathy and wet age-related macular degeneration (wet AMD). Our team of experts has developed this model with consistent results in in the Dutch Belted rabbit.