top of page

Corneal Disease

Corneal disease refers to a variety of conditions that affect the cornea, the clear, dome-shaped tissue that covers the front of the eye. The cornea plays a critical role in visual acutiy.

Cornea Nerves.jpg

Neuropathic Keratitis

The neuropathic keratitis model is used in rodents to evaluate the efficacy of test articles that prevent the loss of corneal sensation and persistent epithelial defects that can progress to more severe complications. Our team of experts has developed reproducible models with consistent results in mice and rats.

DWEK and DMEK

Descemet's Membrane Endothelial Keratoplasty (DMEK) and Descemet's Membrane Endothelial Keratoplasty without Endothelial Keratoplasty (DWEK) are advanced corneal transplantation techniques specifically targeting the endothelial layer of the cornea.This rabbit model is used to evaluate therapies targeting Fuchs’ dystrophy with consistent results.  

Corneal Transplantation

The corneal transplantation surgical model is used in rabbits to evaluate test articles that prevent rejection of donor grafts. The model replaces a damaged or diseased cornea with a healthy donor cornea and has demonstrated consistent, reproducible results.

Infectious Keratitis 

 Infectious keratitis model in rabbits is used to evaluate test articles that treat the serious condition caused by bacteria, viruses, fungi, or parasites, each requiring specific treatment strategies. 

Logo.jpg

At Powered Research with a collaborative mindset and deep technical expertise, we seamlessly impact our Sponsors’ research and development pipelines, transforming discoveries into validated product candidates. Guided by integrity, excellence, and a commitment to making a meaningful impact, we strive to advance scientific progress and deliver real-world solutions. 

 

Please contact us at info@poweredresearch.com to learn how we can help grow your company.​​

Powered Research is proudly located in Research Triangle Park, NC

poweredresearch.com

  • LinkedIn

984-884-4928

bottom of page