Pharmacology

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Pharmacology

As a specialized leader in the development of ocular pharmacology models, Powered Research can help you to assess the efficacy of your drug product or device candidates. Pharmacology models can be used to differentiate between formulations, active pharmaceutical ingredients, or device iterations, enabling you to choose the most effective product to move forward in development. Powered Research offers more than 15 nonclinical animal efficacy models, each of which is specifically designed to assess the therapeutic efficacy in an ophthalmic disease state, condition, or surgical intervention. Our models are supported by our team of ophthalmic experts, as well as our collection of precise instrumentation, ensuring that our studies are conducted correctly and provide relevant data.
Models include:

IAnterior Chamber Inflammation (paracentesis, corneal incision; rabbit)


IChoroidal Neovascularization (laser; rodent, rabbit, and swine)


ICorneal Wound Healing (alkali, scrape, abrasion; rabbit)


IExperimental Autoimmune Uveitis (rat, rabbit)


IEndotoxin-Induced Uveitis (rat, rabbit)


IOxygen-Induced Retinopathy (mouse)


IPhacoemulsification Surgery (rabbit)


IRetinal Leakage and Neovascularization (VEGF; rabbit)


IChronic retinal neovascularization (diabetic retinopathy) (rabbit)


IAllergic Conjunctivitis (Guinea pig)


IRetinitis pigmentosa (Royal College of Surgeons rat)


INormotensive IOP/glaucoma (rat, rabbit, canine)


ICorneal Transplant (rabbit)


IDry eye (mouse, rat, rabbit)


IDMEK/DSEK Surgical model (rabbit)


ITargeted drug/device delivery (subretinal, IVT, IC, subconjuntival)

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