Assessing the ocular drug distribution and pharmacokinetics of your active molecule following dosing is a critical regulatory dataset, and guides decisions for pharmacodynamics (PD) studies. Studies are conducted in rodents, rabbits, canines or swine, and include additional in-vivo endpoints, such as systemic exposure in plasma or serum.
Our experts us a comprehensive ocular dissection technique that ensures each tissue matrix is collected correctly and minimizes the chance of cross-contamination. Powered Research also offers tissue homogenization, allowing for the appropriate preparation of tissue matrices prior to bioanalytical assessment.
Ocular matrices collected include: