Pharmacokinetics (PK)

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Pharmacokinetics (PK)

Assessing the ocular drug distribution and pharmacokinetics of your active molecule following dosing is a critical regulatory dataset, and guides decisions for pharmacodynamics (PD) studies. Studies are conducted in rodents, rabbits, canines or swine, and include additional in-vivo endpoints, such as systemic exposure in plasma or serum.
Our experts us a comprehensive ocular dissection technique that ensures each tissue matrix is collected correctly and minimizes the chance of cross-contamination. Powered Research also offers tissue homogenization, allowing for the appropriate preparation of tissue matrices prior to bioanalytical assessment.
Ocular matrices collected include:

IConjunctiva


ICornea


IAqueous Humor


IIris/Ciliary Body


ILens


IVitreous Humor


IRetina


IChoroid/RPE


IOther tissues upon request

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